Leinster open their URC campaign against Stormers in Cape Town on Friday night.
Luke McGrath captains the side as Leinster kick-off their URC title defence. Academy prop Andrew Sparrow is in line to make his senior debut off the bench.
Sam Prendergast partners McGrath in the half-backs, with Ciarán Frawley and Robbie Henshaw forming a partnership in midfield.
Jordan Larmour and Tommy O'Brien have been named on the wings with Jimmy O'Brien given the nod at full-back.
In the pack, Jack Boyle and Rabah Slimani will scrum down either side of Gus McCarthy, while Diarmuid Mangan and Brian Deeny add their power from the second row.
Ryan Baird takes the number six shirt, with Scott Penny named at openside flanker and James Culhane completing the line up at number eight.
Sparrow and Paddy McCarthy are the props in reserve with John McKee providing cover at hooker. Max Deegan and Will Connors offer their experience to round out the forward replacements.
Harry Byrne, who has returned from his loan spell with Bristol Bears, joins Fintan Gunne and Hugh Cooney in providing the reinforcements for the backline.
Leinster: 15. Jimmy O'Brien, 14. Tommy O'Brien, 13. Robbie Henshaw, 12. Ciarán Frawley, 11. Jordan Larmour, 10. Sam Prendergast, 9. Luke McGrath (C), 1. Jack Boyle, 2. Gus McCarthy, 3. Rabah Slimani, 4. Diarmuid Mangan, 5. Brian Deeny, 6. Ryan Baird, 7. Scott Penny, 8. James Culhane.
Replacements: 16. John McKee, 17. Paddy McCarthy, 18. Andrew Sparrow, 19. Max Deegan, 20. Will Connors, 21. Fintan Gunne, 22. Harry Byrne, 23. Hugh Cooney.
Referee: Gianluca Gnecchi (FIR)