Rescue teams have been working through the night in Turkey and Syria to try to reach people trapped under flattened concrete and twisted metal.
The death toll from two earthquakes has now exceeded 4,000 with tens of thousands more displaced.
With whole neighbourhoods destroyed, the Turkish government says more than 300-thousand people are sheltering in dormitories and universities.
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UNICEF says children are always among the most vulnerable when disaster strikes.
The organisation says an immediate global response is a must in order to save lives.
