Motorists are advised to expect significant traffic in Athlone and surrounding areas ahead of a protest being staged today.
The protest is in opposition to the Mercosur trade deal and a traffic management plan will be in place throughout the day.
More than a thousand tractors and lorries have pre-registered for the protest taking place in Athlone at 11am.
An Garda Síochána understands the public assembly will involve a convoy of tractors from the N61 Roscommon Road, along the N6 travelling eastbound from Junction 12 to Junction 10, and along the N55 towards the R916 Cornamaddy roundabout.
A march is also expected along the R916 to TUS Athlone, where the demonstration will culminate with a rally and speeches from representatives.
Gardaí are advising motorists there will be additional traffic, including slow-moving vehicles, in the N6 area in the morning and over the course of the day.
The N6 is not intended to be closed, however drivers are asked to plan their journeys in advance and to expect localised delays