Johnny Sexton has failed to recover from a calf injury in time for Leinster’s Heineken European Champions cup game with Toulouse.
Ross Byrne starts for Leinster at out-half in Sexton’s place as Jordan Larmour takes the number 15 jersey with Adam Byrne and Dave Kearney on the right and left wing.
Rory O’Loughlin and Garry Ringrose are again the centre partnership having played together in the Munster game over Christmas.
In the half backs Luke McGrath is partnered with Ross Byrne. The front row sees Cian Healy, Seán Cronin and Tadhg Furlong scrum down with Scott Fardy and James Ryan behind in the engine room.
The back row features Captain Rhys Ruddock, Josh van der Flier and Jack Conan at No. 8.
On the bench Conor O’Brien is in line to make his European debut having impressed over the last few months in the Guinness PRO14.
Leinster: Jordan Larmour, Adam Byrne, Garry Ringrose, Rory O’Loughlin, Dave Kearney, Ross Byrne, Luke McGrath, Cian Healy, Sean Cronin, Tadhg Furlong, Scott Fardy, James Ryan, Rhys Ruddock (Captain), Josh van der Flier, Jack Conan
Replacements: James Tracy, Ed Byrne, Andrew Porter, Ross Molony, Max Deegan, Jamison Gibson-Park, Noel Reid, Conor O’Brien
Referee: Luke Pearce (RFU)
Leinster v Toulouse
Saturday January 12
RDS, Kick off 1pm